CuraMed® (750 mg)

About CuraMed®

A patent-pending method using small particle size, turmeric essential oils, and phospholipids ensures that CuraMed® delivers a curcumin that is up to 10 times more bioavailable than cucumin 95%, and 6.3 times more bioavailable than curcumin with lectithin and piperine, as well has having an 8-12 hour retention time in the body. The result is a high-potency formula providing superior support for the body’s natural anti- inflammatory response, a healthy immune and cardiovascular system, and resistance to free radical activity.*

How CuraMed® Works

While the health benefits of curcumin, the active compound from the Indian spice known as turmeric, have been well-documented, it is also well-known that curcumin is not well-absorbed when taken orally (by mouth). Different methods have been used to increase absorption, including combining curcumin with lecithin or piperine (black pepper). The best absorption has been achieved when micronized (very small particles) curcumin is combined with turmeric oils and phospholipids. This combination is 6.9 times more absorbable than regular curcumin, and 6.3 times better absorbed than curcumin with lecithin and piperine.

Curcumin

Curcumin, a compound found in the spice turmeric, inhibits multiple inflammation pathways in the body. It is also a potent antioxidant. Some of the benefits associated with curcumin include immune system modulation, protection from oxidative stress, and support for the body’s natural anti-inflammatory response.* The specialized extract in this formula has the highest absorption of any curcumin extract available for maximum health benefits.

Curcuminoids are a group of biomolecules derived from the Indian spice called Tumeric. The main Cuminoid which possesses powerful anti-inflammatory and health promoting properties is Curcumin Europharma has selected a specific curcuminoid that has been concentrated 100 times making it EXTREMELY POTENT and more absorbable from the intestinal tract. Curcumin exhibits its anti-inflammatory activity by stopping specific molecules that are involved in the inflammatory process

Curcumin inhibits:

	Phospholipase A2 An enzyme that ignites inflammation
	Lipooxygenase An enzyme that produces inflammatory molecules called Leukotrienes
	Leukotrienes Violent and toxic inflammatory molecules that cause damage and pain
	Cyclo-oxygenase-2 The enzyme responsible for producing inflammatory prostaglandins
	Thromboxane A molecular structure that causes the blood to thicken in response to inflammation
	Nitric Oxide A vasoactive molecule that causes redness and swelling with inflammation
	NFkb This is a transcription factor that codes for pro-inflammatory molecules. This is one of the spark plugs that initiates the inflammation process

References

1. Jurenka JS. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev. 2009;14(2):141-53.

2. Jacob A, Wu R, Zhou M, Wang P. Mechanism of the Anti-inflammatory Effect of Curcumin: PPAR-gamma Activation. PPAR Res. 2007;89369.

3. Johnson SM, Gulhati P, Arrieta I, et al. Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling. Anticancer Res. 2009;29(8):3185-90.

4. Ravindran J, Prasad S, Aggarwal BB. Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J. 2009;11(3):495-510.

5. Seehofer D, Schirmeier A, Bengmark S, et al. Curcumin Attenuates Oxidative Stress and Inflammatory Response in the Early Phase after Partial Hepatectomy with Simultaneous Intraabdominal Infection in Rats. J Surg Res. 2008 Dec 31.

6. Biswas S, Rahman I. Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin. Mol Nutr Food Res. 2008;52(9):987-94.

7. Benny B, Antony B. Bioavailability of Biocurcumax (BCM-95). Spice India. September, 2006:11-15.